| Week of | Song | Artist | # in Order |
| January 5, 2010 | Number One | R. Kelly featuring Keri Hilson | |
| January 12, 2010 | Wasted | Gucci Mane featuring Plies or OJ da Juiceman | |
| January 19, 2010 | Bulletproof | Raheem DeVaughn featuring Ludacris | 128 |
| January 26, 2010 | |||
| February 2, 2010 | |||
| February 9, 2010 | |||
| February 16, 2010 | |||
| February 23, 2010 | |||
| March 2, 2010 | BedRock | Young Money featuring Lloyd | 129 |
| March 9, 2010 | Papers | Usher | 130 |
| March 16, 2010 | |||
| March 23, 2010 | Knockin' Your Heels | H-Town featuring K-Ci, JoJo, DeVante & Dalvin (Jodeci) |
131 |
| March 30, 2010 | Papers | Usher | |
| April 6, 2010 | |||
| April 13, 2010 | |||
| April 20, 2010 | Please Excuse My Gas | Keith From Up Da Block | 132 |
| April 27, 2010 | |||
| May 4, 2010 | My Chick Bad | Ludacris featuring Nicki Minaj | 133 |
| May 11, 2010 | Please Excuse My Gas | Keith From Up Da Block | |
| May 18, 2010 | My Chick Bad | Ludacris featuring Nicki Minaj | |
| May 25, 2010 | |||
| June 1, 2010 | Papers | Usher | |
| June 8, 2010 | |||
| June 15, 2010 | |||
| June 22, 2010 | |||
| June 29, 2010 | |||
| July 6, 2010 | Hood Sex | Keith Sweat | 134 |
| July 13, 2010 | |||
| July 20, 2010 | |||
| July 27, 2010 | |||
| August 3, 2010 | |||
| August 10, 2010 | |||
| August 17, 2010 | |||
| August 24, 2010 | |||
| August 31, 2010 | Ridin' Solo | Keith Sweat | 135 |
| September 7, 2010 | |||
| September 14, 2010 | Do Wrong Tonight | Keith Sweat | 136 |
| September 21, 2010 | Hood Sex | Keith Sweat | |
| September 28, 2010 | |||
| October 5, 2010 | |||
| October 12, 2010 | |||
| October 19, 2010 | Sex Room | Ludacris featuring Trey Songz | 137 |
| October 26, 2010 | |||
| November 2, 2010 | |||
| November 9, 2010 | |||
| November 16, 2010 | Lay It Down | Lloyd | 138 |
| November 23, 2010 | |||
| November 30, 2010 | Love All Over Me | Monica | 139 |
| December 7, 2010 | |||
| December 14, 2010 | |||
| December 21, 2010 | |||
| December 28, 2010 |
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